We are in constant pursuit of breakthroughs that improve patients' lives. We innovate daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, recruit and maintain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.