Dopamine controls Parkinson’s tremor by inhibiting the cerebellar thalamus

Fri, 25 Sep 2020 05:45:07 +0000

READ THE PAPER AT: http://bit.ly/2j7yt1c
The dopaminergic basis of Parkinson’s resting tremor is disputed. Using functional MRI network analyses, Dirkx et al. report that that dopamine reduces tremor by selectively inhibiting the cerebellar thalamus. This effect correlated with the clinical dopamine-response. They propose that dopaminergic projections to the cerebellar thalamus control tremulous activity in this region.